Basic Information
VIS ID
TVIS44008240
Fusion event
HTLV-1-LOC101929095 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p15.32
Reference genome
GRCh37/hg19
Start
15254289/15252665 (Hg38)
End
15254289/15252665 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA4D
Target gene
LOC101929095
Nearest miRNA
hsa-mir-12113/Upstream/1624708; hsa-mir-12115/Downstream/5275610;
Nearest TSS
ENST00000502981/Upstream/24705; ENST00000510958/Downstream/87153;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/247528, chr4-CpG: 145/Downstream/402076
Upstream sequence
cacacacTACTGCTGAATTTCCAGGTCATATTTGGCAGACTAGTTAAGGAAGCACTGTGTACATGTTAGCTACCTTGGACCTTGAGTTGCTGCCAGGTTT
Downstream sequence
TATGCTACAGAAAATGTAGTGTGGCTGGAAATGTAGCTCTACTGAAAACTGACCAACCCTGTGTAATATATCCATTTGTTTCGTCATAAAGGAAAGAGTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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