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TVIS44008247
Basic Information
VIS ID
TVIS44008247
Fusion event
HTLV-1-SPATA5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q28.1
Reference genome
GRCh37/hg19
Start
124165968/123244813 (Hg38)
End
124165968/123244813 (Hg38)
Orient
+
Location type
Intronic
Target gene
SPATA5
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-345-3p
;
hsa-mir-186-5p
;
hsa-mir-489-3p
;
hsa-mir-670-5p
;
hsa-mir-4732-3p
;
hsa-mir-6719-3p
;
hsa-mir-8066
;
hsa-mir-5706
;
hsa-mir-4782-5p
;
hsa-mir-1257
;
hsa-mir-3913-3p
;
hsa-mir-6839-5p
;
hsa-mir-378j
;
hsa-mir-4319
;
hsa-mir-125b-5p
;
hsa-mir-125a-5p
;
hsa-mir-6866-3p
;
hsa-mir-188-5p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-7977
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-24-3p
;
hsa-mir-3934-3p
;
hsa-mir-2467-5p
;
hsa-mir-3934-5p
;
hsa-mir-764
;
hsa-mir-125a-3p
;
hsa-mir-383-3p
;
hsa-mir-6748-5p
;
hsa-mir-4483
;
hsa-mir-1293
;
hsa-mir-6766-5p
;
hsa-mir-6756-5p
;
hsa-mir-6745
;
hsa-mir-363-5p
;
hsa-mir-6811-5p
;
hsa-mir-6516-5p
;
hsa-mir-4722-5p
;
hsa-mir-6511b-5p
;
hsa-mir-1286
;
hsa-mir-873-5p
;
hsa-mir-2276-3p
;
hsa-mir-3121-5p
;
hsa-mir-6787-3p
;
hsa-mir-1304-3p
;
hsa-mir-6827-3p
;
hsa-mir-6736-3p
;
hsa-mir-340-3p
;
hsa-mir-6890-3p
;
hsa-mir-216a-5p
;
hsa-mir-6769a-5p
;
hsa-mir-6769b-5p
;
hsa-mir-4284
;
hsa-mir-3123
;
hsa-mir-3151-3p
;
hsa-mir-3192-3p
;
hsa-mir-3919
;
hsa-mir-4756-3p
;
hsa-mir-4762-3p
Nearest miRNA
hsa-mir-12113/Upstream/8587959; hsa-mir-1305/Downstream/2262446;
Nearest TSS
ENST00000502981/Upstream/321712;
ENST00000515726/Downstream/151982;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/321530
,
chr4-CpG: 179/Downstream/152339
Upstream sequence
ATATGTAATGAGTTAAAAACCTTAGTTATCCAGAAACATATTCTGAGCAACATGTTTTTGGTACCACCTGCTGTCTTATATATTTCTTGTCTGCATGCTT
Downstream sequence
CTGTATACCTAGTAGGTGTCTGTAGGCAGATCACCTTACATTGTGATTTCTTTTAAATTGGGAAAAAATATATGTCCTTTGAATATCTTATGGTTCAGCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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