Basic Information
VIS ID
TVIS44008261
Fusion event
HTLV-1-LINC02351 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
98930951/98387722 (Hg38)
End
98930951/98387722 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02351
Nearest miRNA
hsa-mir-10393/Upstream/2054415; hsa-mir-1302-10/Downstream/396704;
Nearest TSS
ENST00000557528/Upstream/60228; ENST00000558355/Downstream/98175;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/426303, chr15-CpG: 68/Downstream/33656
Nearby gene
FAM169B(-49440) ;
Upstream sequence
ACATTTTCAAAAAAAAATTATATCAAAGATCAAGTTTCATCGTATATGCTAAGTGGTAAGTGCTAATGTGTGCATAAATACACACATACATGTAGATGCA
Downstream sequence
TACACTGAAAATATATCTATGGAAATCTGTAAAGAAGCCAGAATTTTCTCATCTTTGACTTTGTCATTTGTCTGGAAGAACCAAATGACAGGAAATTCAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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