Basic Information
VIS ID
TVIS44008341
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p13
Reference genome
GRCh37/hg19
Start
2434465/2453819 (Hg38)
End
2434465/2453819 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-6869/Upstream/1060858; hsa-mir-1-1/Downstream/198958;
Nearest TSS
ENST00000382410/Upstream/59367; ENST00000644205/Downstream/16913;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/50029, chr20-CpG: 47/Downstream/16610
Nearby gene
SNRPB(-7816) ;
Upstream sequence
TCCTGTCAACTAGTATTTGCTGACATAACCTACATGAAGCATTGTGTGTGGGCTTCAATACAAGGCATCActccctcaaaccattttggacctgctaggg
Downstream sequence
agcctgccctgctctccccagaaagcctcatgatgtcagtcttttcatgcctcttggtgcatgtgtagaatcctccgtGGCAGATGACCAACCACAGTTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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