Basic Information
VIS ID
TVIS44008352
Fusion event
HTLV-1-LOC105374020 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
104155414/104436570 (Hg38)
End
104155414/104436570 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105374020
Nearest miRNA
hsa-let-7g/Upstream/912454; hsa-mir-12124/Downstream/5166258;
Nearest TSS
ENST00000440867/Upstream/1762657; ENST00000470756/Downstream/930339;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/2586368, chr3-CpG: 32/Downstream/917115
Nearby gene
MIR548A3(No orient, 209309)
Upstream sequence
AAAGACTGCTAGAAATTTTGCAGAGACTCTGCTTGTGTTACTTTGTTTTACTCTCTAAGGTAAAAGCCTGTAATTGGGCCCAACTTACCAAGTTACATGT
Downstream sequence
AACCTAAATTTTGGAGCAGATTTAATTCCCTGACATATACCAGGGTACAGATAAGTAGTGTCAAAGAGTATAAACCCAGATGGCTAAATCCAGAATCATA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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