Basic Information
VIS ID
TVIS44008377
Fusion event
HTLV-1-LOC112267976 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
80045191/79335474 (Hg38)
End
80045191/79335474 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC112267976
Nearest miRNA
hsa-mir-10398/Upstream/796165; hsa-mir-1202/Downstream/10977268;
Nearest TSS
ENST00000381078/Upstream/100736; ENST00000429444/Downstream/84823;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/100641, chr6-CpG: 43/Downstream/201718
Nearby gene
LCAL1(No orient, 22090)
Upstream sequence
TGTGACTGAGAAATTTATGTCAGAGAGTAATCCAGAAATGAGGTCAGCCTTTTCTCTGCTGGGGAGGGCCATTGAGCTATTGAGAATCTGTGTTATTACC
Downstream sequence
ATTCCATTCAGTTCCTCTTTTAAGAACTAACTTAATAAGCTCCACTGGGCAAGTCTATTAACATCCCCTTCTACCACGACGGGTCTTTCCAAAGTGGAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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