Basic Information
VIS ID
TVIS44008417
Fusion event
HTLV-1-LOC101929408 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
76054929/75762588 (Hg38)
End
76054929/75762588 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC101929408
Nearest miRNA
hsa-mir-10393/Upstream/273; hsa-mir-11181/Downstream/3447200;
Nearest TSS
ENST00000557528/Upstream/183; ENST00000562635/Downstream/80697;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/23247, chr15-CpG: 135/Downstream/80382
Nearby gene
MIR4313(-273) ;
Upstream sequence
GCGCCCCCTGCCAAGGCCTTCTGCAAACACTCCCCAGGGGCTGTTGTGGGCAGCACCTGGGTGGTGCAGTTGGTGTGCCAGAAAAGCTCCCCAGTACTGG
Downstream sequence
GCAGTGGCCCAGGCAGTCAAGCAGACTCCCTCAAGCAGGCCCCACCTACCCCTCGCCTGTTCCCAGCTGCCTCCCACCAACCCTAGAAATGATGCTGGGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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