Basic Information
VIS ID
TVIS44008436
Fusion event
HTLV-1-OTUD7B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.2
Reference genome
End
149919553/149947652 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-1229-3p ; hsa-mir-877-5p ; hsa-mir-339-5p ; hsa-mir-16-5p ; hsa-mir-500a-5p ; hsa-mir-218-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-638 ; hsa-mir-6499-3p ; hsa-mir-4537 ; hsa-mir-1292-3p ; hsa-mir-4799-5p ; hsa-mir-6892-5p ; hsa-mir-6878-5p ; hsa-mir-5703 ; hsa-mir-4434 ; hsa-mir-4516 ; hsa-mir-658 ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-95-5p ; hsa-mir-154-5p ; hsa-mir-7846-3p ; hsa-mir-6760-5p ; hsa-mir-4475 ; hsa-mir-6874-5p ; hsa-mir-513b-5p ; hsa-mir-6880-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6500-5p ; hsa-mir-4633-3p ; hsa-mir-8077 ; hsa-mir-4765 ; hsa-mir-1236-5p ; hsa-mir-6134 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-3160-3p ; hsa-mir-125b-2-3p ; hsa-mir-4756-5p ; hsa-mir-4457 ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-587 ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-4282 ; hsa-mir-7850-5p ; hsa-mir-6079 ; hsa-mir-4533 ; hsa-mir-4733-5p ; hsa-mir-7703 ; hsa-mir-500a-3p ; hsa-mir-5708 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-6721-5p ; hsa-mir-4663 ; hsa-mir-661 ; hsa-mir-767-5p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-6849-3p ; hsa-mir-939-3p ; hsa-mir-1273g-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-508-5p ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-3202 ; hsa-mir-7160-5p ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-7854-3p ; hsa-mir-7162-3p ; hsa-mir-383-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-548s ; hsa-mir-4684-5p ; hsa-mir-3926 ; hsa-mir-3190-5p ; hsa-mir-3675-3p ; hsa-mir-6771-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-101-1/Upstream/1559289; hsa-mir-1182/Downstream/544693;
Upstream sequence
ctatcctgtagggttgttgtaaagattaaaacagtgtttggaaagagcccagcacagtgtctggaaaatgggaaatactagatagtagccattatcattG
Downstream sequence
TTGTTGTTGTAAATATTATTTAGAAGGAGCTTTTGATAAATAGGTGAGAGGTTATTTTTAAAAAGCCATAAACTCTGGATTTTAAAATCAAACTCTCTTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate