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TVIS44008436
Basic Information
VIS ID
TVIS44008436
Fusion event
HTLV-1-OTUD7B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
149919553/149947652 (Hg38)
End
149919553/149947652 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
OTUD7B
miRNAs that regulate target gene
hsa-mir-1229-3p
;
hsa-mir-877-5p
;
hsa-mir-339-5p
;
hsa-mir-16-5p
;
hsa-mir-500a-5p
;
hsa-mir-218-5p
;
hsa-mir-6516-5p
;
hsa-mir-455-3p
;
hsa-mir-638
;
hsa-mir-6499-3p
;
hsa-mir-4537
;
hsa-mir-1292-3p
;
hsa-mir-4799-5p
;
hsa-mir-6892-5p
;
hsa-mir-6878-5p
;
hsa-mir-5703
;
hsa-mir-4434
;
hsa-mir-4516
;
hsa-mir-658
;
hsa-mir-107
;
hsa-mir-103a-3p
;
hsa-mir-95-5p
;
hsa-mir-154-5p
;
hsa-mir-7846-3p
;
hsa-mir-6760-5p
;
hsa-mir-4475
;
hsa-mir-6874-5p
;
hsa-mir-513b-5p
;
hsa-mir-6880-5p
;
hsa-mir-6851-5p
;
hsa-mir-3689d
;
hsa-mir-6500-5p
;
hsa-mir-4633-3p
;
hsa-mir-8077
;
hsa-mir-4765
;
hsa-mir-1236-5p
;
hsa-mir-6134
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-3160-3p
;
hsa-mir-125b-2-3p
;
hsa-mir-4756-5p
;
hsa-mir-4457
;
hsa-mir-4739
;
hsa-mir-1321
;
hsa-mir-587
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-4698
;
hsa-mir-8063
;
hsa-mir-513c-3p
;
hsa-mir-513a-3p
;
hsa-mir-3606-3p
;
hsa-mir-4282
;
hsa-mir-7850-5p
;
hsa-mir-6079
;
hsa-mir-4533
;
hsa-mir-4733-5p
;
hsa-mir-7703
;
hsa-mir-500a-3p
;
hsa-mir-5708
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-6721-5p
;
hsa-mir-4663
;
hsa-mir-661
;
hsa-mir-767-5p
;
hsa-mir-6860
;
hsa-mir-612
;
hsa-mir-5189-5p
;
hsa-mir-3187-5p
;
hsa-mir-1285-3p
;
hsa-mir-4793-3p
;
hsa-mir-766-3p
;
hsa-mir-6849-3p
;
hsa-mir-939-3p
;
hsa-mir-1273g-3p
;
hsa-mir-92b-3p
;
hsa-mir-92a-3p
;
hsa-mir-367-3p
;
hsa-mir-363-3p
;
hsa-mir-32-5p
;
hsa-mir-25-3p
;
hsa-mir-508-5p
;
hsa-mir-6514-3p
;
hsa-mir-7977
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-3202
;
hsa-mir-7160-5p
;
hsa-mir-6847-3p
;
hsa-mir-6811-3p
;
hsa-mir-214-5p
;
hsa-mir-7854-3p
;
hsa-mir-7162-3p
;
hsa-mir-383-3p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-548s
;
hsa-mir-4684-5p
;
hsa-mir-3926
;
hsa-mir-3190-5p
;
hsa-mir-3675-3p
;
hsa-mir-6771-3p
;
hsa-mir-19b-3p
;
hsa-mir-19a-3p
Nearest miRNA
hsa-mir-101-1/Upstream/1559289; hsa-mir-1182/Downstream/544693;
Nearest TSS
ENST00000473358/Upstream/10783;
ENST00000478999/Downstream/23609;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/19651
,
chr1-CpG: 70/Downstream/62552
Upstream sequence
ctatcctgtagggttgttgtaaagattaaaacagtgtttggaaagagcccagcacagtgtctggaaaatgggaaatactagatagtagccattatcattG
Downstream sequence
TTGTTGTTGTAAATATTATTTAGAAGGAGCTTTTGATAAATAGGTGAGAGGTTATTTTTAAAAAGCCATAAACTCTGGATTTTAAAATCAAACTCTCTTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL181
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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