Basic Information
VIS ID
TVIS44008437
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
172887513/172918373 (Hg38)
End
172887513/172918373 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1G
Nearest miRNA
hsa-mir-101-1/Upstream/773729; hsa-mir-1182/Downstream/3049997;
Nearest TSS
ENST00000473358/Upstream/11473; ENST00000460950/Downstream/132590;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/384968, chr1-CpG: 100/Downstream/558466
Nearby gene
TNFSF18(-122847) ;
Upstream sequence
CAACTTCCTACCACCTCCACCCAGAACAATGAATGGAGTTGAGGTTTTCCCATTTATTCATATCTGGTATCTCTGTGCCAAAGTGACATCCACACAATGT
Downstream sequence
TTTCTCATATTTAAACAACACTGGTCACTTAATTACAGTTTAAAGTTAATTCAAGAGAAGGGCTATATACTAGTAGAAAAATAAGTTTTATCTGGATATT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate