Basic Information
VIS ID
TVIS44008473
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
57530286/57063568 (Hg38)
End
57530286/57063568 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/2185375; hsa-mir-1185-1/Downstream/2583394;
Nearest TSS
ENST00000550708/Upstream/169858; ENST00000554213/Downstream/4974;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/245728, chr14-CpG: 57/Downstream/204820
Nearby gene
OTX2-AS1(No orient, 132736)
Upstream sequence
ACCTTTAAAATCTGCATCTGTATAACAACCACTCCACTAATTAAAAAGTTCAATAAAGCAAGGCTTGTAAGCAAAATAGCAAATAATTGGCCTGGATACT
Downstream sequence
TTTTGACAGAATAGGCCAAACTGCTAGATAAGTTTTAACAGTGCACGTGTGCCTGAGACCTCAGTTAGGCTCCTTTTAGCACAGAATTTTTGGGTTTTCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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