Basic Information
VIS ID
TVIS44008490
Fusion event
HTLV-1-LOC105371750 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
GRCh37/hg19
Start
35080677/36724366 (Hg38)
End
35080677/36724366 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105371750
Nearest miRNA
hsa-mir-1180/Upstream/4374164; hsa-mir-10226/Downstream/309379;
Nearest TSS
ENST00000595228/Upstream/1783; ENST00000619297/Downstream/212256;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/20119, chr17-CpG: 65/Downstream/83707
Nearby gene
MRM1(+115270) ;
Upstream sequence
TCTCCTTGTCTATGTCCGTTTCAGGTTTGTTGATCTGCCTGAATGTCTCTGCATGTGGCCCCACATCTCTCCTCATGCCTGCTGGTCTCAGAGTATAATG
Downstream sequence
GATGCTGAGTCCAAAGCAGGTGTTTCCTGGGCATTCGTGGCAGGGGAATTGGACTTCCAAATCTGCCCCCGCTCCACGTGGGTGAGCTTCTCCCAGACTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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