VISDB Viral Integration Site DataBase

VIS ID

TVIS44008521

Fusion event

HTLV-1-CRNKL1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr20

Cytoband

p11.23

Reference genome

Start

End

20031371/20050727 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-186-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-3613-3p ; hsa-mir-329-5p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-4477a ; hsa-mir-3117-5p ; hsa-mir-628-3p ; hsa-mir-6777-3p ; hsa-mir-126-5p ; hsa-mir-4704-5p ; hsa-mir-3923 ; hsa-mir-944 ; hsa-mir-570-5p ; hsa-mir-548ba ; hsa-mir-548ai ; hsa-mir-548ag ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-548s ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-3926 ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-3190-5p ; hsa-mir-1284 ; hsa-mir-6849-3p ; hsa-mir-8063

Nearest miRNA

hsa-mir-103a-2/Upstream/1580036; hsa-mir-1-1/Downstream/6157459;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/32812, chr20-CpG: 63/Downstream/1369

Upstream sequence

AAGAAAGAAGACATTTCTATTTTTAGTAGTTGCTCTTCACACAAGGCTTAAGAAACAAACATACATTTTTTAGGATATGAACTTTGTTAGTATTATCACA

Downstream sequence

AGATGCCCTTTTTGTATGACATGTTCCCATTCCTCCATGAGACTGAAAAGAAAAAAAAAATACCGTTTTCTCTCTTATTCATAGTATCTACTGCAAAGCC