Basic Information
VIS ID
TVIS44008579
Fusion event
HTLV-1-LOC105379066 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
86711545/87415728 (Hg38)
End
86711545/87415728 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105379066
Nearest miRNA
hsa-mir-10397/Upstream/300774; hsa-mir-103a-1/Downstream/1251125;
Nearest TSS
ENST00000502646/Upstream/2709; ENST00000504287/Downstream/246314;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2667, chr5-CpG: 30/Downstream/725550
Nearby gene
CCNH(-2695) ;
Upstream sequence
AAGAGTATTAGGATTTCCTTTCTCTTGCTTCAGGACAGTCTTCCTTCTTTGCGGTCTACCTAGTGATCTTAATGTTTAGGGAAAAATAAAAGTAAAAAGG
Downstream sequence
TCATATTGCCTGATCTTAGGAGAAAAGGAAGAAAAGGGGAATTAAAAGGTTGTGGGAGTGACCAGTAAATATGTTTGCAACTGAAATAATTTTGCAGTCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate