Basic Information
VIS ID
TVIS44008588
Fusion event
HTLV-1-LOC101928516 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q13
Reference genome
GRCh37/hg19
Start
74841702/74131986 (Hg38)
End
74841702/74131986 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA6D
Target gene
LOC101928516
Nearest miRNA
hsa-mir-10398/Upstream/1164233; hsa-mir-10524/Downstream/1296421;
Nearest TSS
ENST00000381078/Upstream/62535; ENST00000421318/Downstream/463227;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/435575, chr6-CpG: 28/Downstream/953178
Upstream sequence
TATTATCCATTTAATTAGGGACCAGATCTTTAATCTGGTAGTGAGGTACTTGGCAACTTTAAGAGTTGATTGAGTTATTATAGTAAATGGGTTGGAGTAG
Downstream sequence
AGCTTAGTTACAAAGAGTACACATAATTTTTGTCAATGACAATTATATTTTTATGTTTCATCTCCTTGAATCTTGAAATTAAAACCAATTTATAAACAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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