VISDB Viral Integration Site DataBase

VIS ID

TVIS44008648

Fusion event

HTLV-1-MAPK8 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q11.22

Reference genome

Start

End

49548228/48340185 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-199a-3p ; hsa-mir-214-3p ; hsa-mir-421 ; hsa-mir-193b-3p ; hsa-mir-125a-5p ; hsa-mir-140-3p ; hsa-mir-10a-5p ; hsa-mir-33a-5p ; hsa-mir-877-5p ; hsa-mir-92a-3p ; hsa-mir-3163 ; hsa-mir-4480 ; hsa-mir-1277-5p ; hsa-mir-3662 ; hsa-mir-374b-3p ; hsa-mir-548s ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-3926 ; hsa-mir-3190-5p ; hsa-mir-4280 ; hsa-mir-892b ; hsa-mir-193a-3p ; hsa-mir-497-3p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30a-5p ; hsa-mir-3680-3p ; hsa-mir-433-3p ; hsa-mir-7154-5p ; hsa-mir-4795-3p ; hsa-mir-8060 ; hsa-mir-496 ; hsa-mir-664a-3p ; hsa-mir-126-5p ; hsa-mir-203a-3p ; hsa-mir-33b-5p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-4775 ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3613-3p ; hsa-mir-888-5p ; hsa-mir-590-3p ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-4282

Nearest miRNA

hsa-mir-1265/Upstream/3176097; hsa-mir-107/Downstream/645327;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/32828, chr10-CpG: 86/Downstream/109996

Upstream sequence

aagacagctgtgcttgcatgtttgttgcatgcagcactattcacaatagcagaggcacagaatcaagtgttcatcaacagtggattagataaaagaaaat

Downstream sequence

gtggtacatatgcaccatggatactacagagccataatcaggaatgaaataatgtcctttacagcaacgtggatgcagctggaggccattatcaagtgaa