Basic Information
VIS ID
TVIS44008661
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
61760362/61366581 (Hg38)
End
61760362/61366581 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1228/Upstream/3541889; hsa-let-7i/Downstream/893778;
Nearest TSS
ENST00000382841/Upstream/1273717; ENST00000546718/Downstream/460652;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1769855, chr12-CpG: 117/Downstream/824406
Nearby gene
TAFA2(-341667) ;
Upstream sequence
TATTTTTGCATTTTATTATAAAGGATTTAGTCTCACCTTCATTGTTTCATGTACTTTTCTTAGCACTGAGAATGTTCCAGAGCATTGTAATATCAGTTTC
Downstream sequence
TCCTTAAAGATACATTTACAAGTGGGTAGTATAAATTTACACTTCATACTCACTCTTGAGATGTTAATTTTTTACTACTATGATATTTTCCATGTTTTTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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