Basic Information
VIS ID
TVIS44008668
Fusion event
HTLV-1-EDNRB-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
78409702/77835567 (Hg38)
End
78409702/77835567 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA13E
Target gene
EDNRB-AS1
Nearest miRNA
hsa-mir-1297/Upstream/137451; hsa-mir-1267/Downstream/9783098;
Nearest TSS
ENST00000623511/Upstream/7345; ENST00000414743/Downstream/68001;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/136796, chr13-CpG: 70/Downstream/82723
Upstream sequence
TTGTCTTGGCCAGAAATCTAGATGCTGACATCATGGGAAATATCCTTTTAGTTTGATGTATGCATCTTTCTTCAGGGCTCTTTATCCTTTAATACCTAAT
Downstream sequence
TGTTCTACCTTGTTTTTTTTTTTTTTTCATTCCTACTCCTTTTCTTCTACCCCTTAGGTCATATGTATCTATCTTCGTCACAGTCAAGGTGGCCCCTGTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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