Basic Information
VIS ID
TVIS44008686
Fusion event
HTLV-1-LOC105372076 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
36302475/38722511 (Hg38)
End
36302475/38722511 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105372076
Nearest miRNA
hsa-mir-1-2/Upstream/1065296; hsa-mir-122/Downstream/899612;
Nearest TSS
ENST00000575820/Upstream/34513; ENST00000637744/Downstream/591729;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/1154846, chr18-CpG: 34/Downstream/1118985
Nearby gene
MIR924HG(No orient, 484413)
Upstream sequence
TTTCACATTTTCACACTAGCTAGAGAAGAGAAAGTAAAGCTCAGAAAGAGACAATTCAGGAAGAAGTTAATCCATTTAGTCCTTTTTCtccatccatcca
Downstream sequence
ttcatccgccctctgtccatcagtctatccatctatccattcatccatccatctacccaCTGTCTTAGTGCCTTGGAGTTTGGTGGTTTAATTAAATGTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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