Basic Information
VIS ID
TVIS44008691
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
35571123/35346057 (Hg38)
End
35571123/35346057 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1301/Upstream/1927493; hsa-mir-10b/Downstream/125348;
Nearest TSS
ENST00000437798/Upstream/183254; ENST00000428774/Downstream/1009057;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1618440, chr2-CpG: 191/Downstream/1009197
Nearby gene
LINC01320(No orient, 623493)
Upstream sequence
acagaaaacatcatgtacaaaaagcccacagctaatatcatgctaactggtaaaagactgaatgctttccccttaagctcagaaataagaaaaggatacc
Downstream sequence
cactcttattgtgtctatttgacattgtgctagagattctagccagataatttgtttaagaaaaataaataagcaaaaagcatctaagttggaaaggaag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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