Basic Information
VIS ID
TVIS44008703
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
24763966/24783330 (Hg38)
End
24763966/24783330 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/6312639; hsa-mir-1-1/Downstream/1424856;
Nearest TSS
ENST00000382410/Upstream/103783; ENST00000620459/Downstream/148510;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/311929, chr20-CpG: 18/Downstream/134988
Nearby gene
SYNDIG1(+116713) ;
Upstream sequence
ggtgtactacagttgctggttcttgcatctgtctcgactactgaggtctaagccatgggcacgaagacccgcattttactcgctgctgcccatgctgtct
Downstream sequence
cctggcactgagtggtttctctaaaactgtctagtgaatTACTCCAAATTCTACCACTTCTGACTAATGATGGGTGACGCTTAAGACAGAGAAAATCTTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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