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TVIS44008737
Basic Information
VIS ID
TVIS44008737
Fusion event
HTLV-1-CDKAL1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
20871381/20871150 (Hg38)
End
20871381/20871150 (Hg38)
Orient
+
Location type
Intronic
Target gene
CDKAL1
miRNAs that regulate target gene
hsa-let-7b-5p
;
hsa-mir-98-5p
;
hsa-let-7e-5p
;
hsa-mir-1273e
;
hsa-mir-887-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-7160-5p
;
hsa-mir-4722-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-1827
;
hsa-mir-4649-3p
;
hsa-mir-1282
;
hsa-mir-5707
;
hsa-mir-665
;
hsa-mir-4768-3p
;
hsa-mir-5690
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-890
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-6089
;
hsa-mir-6499-5p
;
hsa-mir-5693
;
hsa-mir-500a-5p
;
hsa-mir-583
;
hsa-mir-1276
;
hsa-mir-4311
;
hsa-mir-8081
;
hsa-mir-627-5p
;
hsa-mir-937-5p
;
hsa-mir-3162-5p
;
hsa-mir-4266
;
hsa-mir-7154-3p
;
hsa-mir-1288-3p
;
hsa-mir-202-3p
;
hsa-mir-4500
;
hsa-mir-4458
;
hsa-let-7i-5p
;
hsa-let-7g-5p
;
hsa-let-7f-5p
;
hsa-let-7d-5p
;
hsa-let-7c-5p
;
hsa-let-7a-5p
;
hsa-mir-7162-3p
;
hsa-mir-4756-5p
;
hsa-mir-4739
;
hsa-mir-1321
;
hsa-mir-6760-5p
;
hsa-mir-4779
;
hsa-mir-4695-5p
;
hsa-mir-3169
;
hsa-mir-6840-3p
;
hsa-mir-4459
Nearest miRNA
hsa-mir-3691/Upstream/2299270; hsa-mir-10398/Downstream/6276476;
Nearest TSS
ENST00000381078/Upstream/70456;
ENST00000476517/Downstream/329662;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/467598
,
chr6-CpG: 131/Downstream/716040
Upstream sequence
CACAATTCCAAGGTACTTATTGCACACAAGTAATGCTAACTGATTGAGTGGCATTAACcaattaggagaagtacctgtggatcccttctcatgatgatat
Downstream sequence
ttttaaatgtgtaaaataaaattcataggattaaaagaaagcaagttatattgaaatagcgttatcagtacatgaacattttcgtgatatatgtgcttct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL188
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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