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TVIS44008769
Basic Information
VIS ID
TVIS44008769
Fusion event
HTLV-1-TMTC1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
29712058/29559125 (Hg38)
End
29712058/29559125 (Hg38)
Orient
+
Location type
Intronic
Target gene
TMTC1
miRNAs that regulate target gene
hsa-mir-193b-3p
;
hsa-mir-320a
;
hsa-mir-27b-3p
;
hsa-mir-3157-5p
;
hsa-mir-1238-3p
;
hsa-mir-6749-3p
;
hsa-mir-670-3p
;
hsa-mir-6792-3p
;
hsa-mir-4691-5p
;
hsa-mir-627-3p
;
hsa-mir-5695
;
hsa-mir-4666a-3p
;
hsa-mir-7849-3p
;
hsa-mir-3910
;
hsa-mir-374b-5p
;
hsa-mir-374a-5p
;
hsa-mir-655-3p
;
hsa-mir-374c-5p
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-369-3p
;
hsa-mir-335-3p
;
hsa-mir-1305
;
hsa-mir-607
;
hsa-mir-3613-3p
;
hsa-mir-561-3p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-548p
;
hsa-mir-887-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-6778-5p
;
hsa-mir-1233-5p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-6894-5p
;
hsa-mir-7160-5p
;
hsa-mir-6134
;
hsa-mir-7854-3p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-7162-3p
;
hsa-mir-5088-3p
;
hsa-mir-665
;
hsa-mir-4691-3p
;
hsa-mir-6866-3p
;
hsa-mir-188-5p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-4661-3p
;
hsa-mir-890
;
hsa-mir-4715-3p
;
hsa-mir-3064-3p
;
hsa-mir-548aw
;
hsa-mir-19b-3p
;
hsa-mir-19a-3p
;
hsa-mir-1468-3p
;
hsa-mir-125b-2-3p
;
hsa-mir-454-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-301b-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-130a-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-6776-3p
;
hsa-mir-497-3p
;
hsa-mir-548t-3p
;
hsa-mir-548ap-3p
;
hsa-mir-548aa
Nearest miRNA
hsa-mir-1244-3/Upstream/3685046; hsa-let-7i/Downstream/12764575;
Nearest TSS
ENST00000382841/Upstream/39394;
ENST00000549055/Downstream/45099;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/169220
,
chr12-CpG: 145/Downstream/223937
Upstream sequence
AACCATCAGAAGATTTAAGGGTTGTCCCATGCACATGATGAAGCCAATTTCCATATTCCTTATTTCCTTTACAACAAGCAGTAACAGAAAGCTTATCTGG
Downstream sequence
GACATGTGTCTTCCTTTTTCGTAGAGGAAATAATTTCTTAAGACGTTCTCTTTTTCTTATTTATTTAAGGCTCTGAGCCCTTGAAATGAACTTCTGAGGT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL210
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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