Basic Information
VIS ID
TVIS44008774
Fusion event
HTLV-1-GAPDHP23 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p12
Reference genome
GRCh37/hg19
Start
120004814/119462191 (Hg38)
End
120004814/119462191 (Hg38)
Orient
-
Location type
Intronic
Target gene
GAPDHP23
Nearest miRNA
hsa-mir-101-1/Upstream/2367463; hsa-mir-1182/Downstream/26388396;
Nearest TSS
ENST00000473358/Upstream/44778; ENST00000487520/Downstream/45007;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/134279, chr1-CpG: 134/Downstream/160488
Nearby gene
HSD3B2(+39152) ;
Upstream sequence
GTCATACCAGAAAATGAGCTTGAGAAAGTGGTCACTGAGGGCAATGACAGCCCCAGGATCAAAGGTGGAAGAGTGGGTGTCAATGGTTAAGCTGAAGTAG
Downstream sequence
ACAACCTAGTGCTCAGTGTAGCACAGGATGCCCTTGAGGGGATCCTCTGATGTCTGCTTCACCACCTTCTTGATGTTATATTTGGCAGGTTTTTCCAGAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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