Basic Information
VIS ID
TVIS44008781
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
125384292/125665448 (Hg38)
End
125384292/125665448 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/513896; hsa-mir-12124/Downstream/124956;
Nearest TSS
ENST00000440867/Upstream/70358; ENST00000610060/Downstream/109266;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/69767, chr3-CpG: 82/Downstream/100927
Nearby gene
OSBPL11(-69911) ;
Upstream sequence
cttctaaaatatcattttttggattatacaaAACTTAAGCTTGGATCTTTTATAATGAAAACACATTTTATTCAGTGATATAAAACAGCAAATTAGGTGG
Downstream sequence
CAcacagtggctcacgcctgtaatcccagtactttgggaggctgaggcaggtaggcagatcacttgaattcaggagttcgagacctgcctggccaacatg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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