VISDB Viral Integration Site DataBase

VIS ID

TVIS44008791

Fusion event

HTLV-1-PLXDC2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

p12.31

Reference genome

Start

End

20394655/20105726 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-148b-3p ; hsa-mir-1-3p ; hsa-mir-181a-5p ; hsa-let-7b-5p ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-3152-3p ; hsa-mir-4635 ; hsa-mir-4694-5p ; hsa-mir-574-5p ; hsa-mir-1277-5p ; hsa-mir-599 ; hsa-mir-3912-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-6755-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-198 ; hsa-mir-193a-5p ; hsa-mir-1273f ; hsa-mir-1304-3p ; hsa-mir-4781-3p ; hsa-mir-5011-5p ; hsa-mir-3976 ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-302f ; hsa-mir-3675-3p ; hsa-mir-136-3p ; hsa-mir-5698 ; hsa-mir-744-3p ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-3622b-5p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-3194-3p ; hsa-mir-6499-3p ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-103b ; hsa-mir-5693 ; hsa-mir-7705 ; hsa-mir-617 ; hsa-mir-3605-3p ; hsa-mir-8087 ; hsa-mir-6854-5p ; hsa-mir-6885-3p ; hsa-mir-147a ; hsa-mir-5010-3p ; hsa-mir-6818-5p

Nearest miRNA

hsa-mir-1265/Upstream/2260533; hsa-mir-107/Downstream/446244;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/287709, chr10-CpG: 149/Downstream/1067473

Upstream sequence

GCTGTAGTCTCTCCTCCTGCCCCCTACCCCCACCTCACCTTTCTCTCTGCAGCAACCCGGAGCAAGTTTCTCAAAGGAAGCTGAAATGGGTATCACCTTG

Downstream sequence

GTTGTCAGGCTCTCAACATCCTCATTAAGAACCTTCTAGTGACGGGCCTGGTGCCTTGTGAGATCATCACATTCAgagccacactcggtacaaatcctcg