Basic Information
VIS ID
TVIS44008824
Fusion event
HTLV-1-LINC00907 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
40184436/42604471 (Hg38)
End
40184436/42604471 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC00907
Nearest miRNA
hsa-mir-1-2/Upstream/2927692; hsa-mir-122/Downstream/2365611;
Nearest TSS
ENST00000575820/Upstream/378507; ENST00000591940/Downstream/369624;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/2762606, chr18-CpG: 180/Downstream/2074547
Upstream sequence
TATCCTTTTTTAGCAAATAAATGTCTATATGCATGCTTGTCTCTAGTCTGTCAATTCAGCACTTAAATTGATTTGCCTTTTTTAAAAAAGAAAAATATCA
Downstream sequence
GTGGGAACAAAGGAAGCGATCAATTTTACATCAATGAAAGAGCTAAGGTTTCACCTTCTAGTCGGATTACTTCTGCACATCACTTTTGAAAAGGTAGTTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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