Basic Information
VIS ID
TVIS44008828
Fusion event
HTLV-1-LOC105374464 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
37829926/37602783 (Hg38)
End
37829926/37602783 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105374464
Nearest miRNA
hsa-mir-1301/Upstream/2131297; hsa-mir-10b/Downstream/9774892;
Nearest TSS
ENST00000437798/Upstream/2647; ENST00000431712/Downstream/44875;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/257529, chr2-CpG: 167/Downstream/68216
Nearby gene
CDC42EP3(-39099) ;
Upstream sequence
gtgcctgataattttaatatctgaattagttttgtctttttccctctggtttttcagacagtagtctgatattatggtttgttttgtaaattttgattga
Downstream sequence
gtccagacattatatgtgagaaaattaaagtgacaagttgaaagtggaggctcacaataaggtttccttcctccagtgagggtttagaacagaaagtgat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate