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Viral Integration Site DataBase
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TVIS44008842
Basic Information
VIS ID
TVIS44008842
Fusion event
HTLV-1-LSAMP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
115660319/115941472 (Hg38)
End
115660319/115941472 (Hg38)
Orient
+
Location type
Intronic
Target gene
LSAMP
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-26b-5p
;
hsa-mir-369-3p
;
hsa-mir-5584-3p
;
hsa-mir-552-5p
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6875-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-5006-3p
;
hsa-mir-4755-5p
;
hsa-mir-3977
;
hsa-mir-6873-3p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-623
;
hsa-mir-103a-2-5p
;
hsa-mir-302d-5p
;
hsa-mir-302b-5p
;
hsa-mir-942-5p
;
hsa-mir-4680-3p
;
hsa-mir-6845-3p
;
hsa-mir-6832-3p
;
hsa-mir-345-3p
;
hsa-mir-3162-3p
;
hsa-mir-3150b-5p
;
hsa-mir-3150a-5p
;
hsa-mir-6756-3p
;
hsa-mir-4469
;
hsa-mir-4667-3p
;
hsa-mir-1470
;
hsa-mir-6749-3p
;
hsa-mir-6792-3p
;
hsa-mir-4691-5p
;
hsa-mir-6818-3p
;
hsa-mir-6888-3p
;
hsa-mir-593-3p
;
hsa-mir-6895-3p
;
hsa-mir-630
;
hsa-mir-3120-5p
;
hsa-mir-4742-3p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-361-3p
;
hsa-mir-4778-5p
;
hsa-mir-629-3p
;
hsa-mir-4279
;
hsa-mir-6867-3p
;
hsa-mir-4713-5p
;
hsa-mir-6868-3p
;
hsa-mir-6763-3p
;
hsa-mir-5581-5p
;
hsa-mir-4297
;
hsa-mir-3124-3p
;
hsa-mir-1976
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-7113-3p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-660-3p
;
hsa-mir-3127-3p
;
hsa-mir-553
;
hsa-mir-4762-3p
;
hsa-mir-29b-2-5p
;
hsa-mir-4256
;
hsa-mir-6719-3p
;
hsa-mir-4526
;
hsa-mir-3660
;
hsa-mir-6730-3p
;
hsa-mir-296-3p
;
hsa-mir-192-3p
;
hsa-mir-342-3p
Nearest miRNA
hsa-let-7g/Upstream/1197947; hsa-mir-12124/Downstream/908805;
Nearest TSS
ENST00000440867/Upstream/88894;
ENST00000490351/Downstream/109780;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/156738
,
chr3-CpG: 75/Downstream/2055245
Nearest cancer related gene
LSAMP
(TSG, No orient, 0)
Upstream sequence
tcaaaaattaaaaacaaaactaccatatgatccagcaatcccacttcttggtatgtatccaaaggaaatgaaattattaccttgaaaagttatctgtacc
Downstream sequence
gccatgttcactgcagcattaacaatcaccaacatatggaaacagcttaaatgtccatcaacagataaatgtatttaaaaattggcgcacacacacacag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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