Basic Information
VIS ID
TVIS44008871
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
82793696/83164380 (Hg38)
End
82793696/83164380 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10525/Upstream/7249111; hsa-mir-10399/Downstream/9039635;
Nearest TSS
ENST00000635602/Upstream/1450; ENST00000430696/Downstream/190774;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1284, chr7-CpG: 30/Downstream/585189
Nearby gene
PCLO(-1499) ;
Upstream sequence
TCCTTCCTAACAGAAGGTGAGAGAGGATTGTGTTCATTGAGTGGAGCAAGAACCTGCAGTGGCTTAAGGTCCGACGCTTCATTTTTTGTTAAGGCCGAGT
Downstream sequence
TACTTCTGAATTGCTGCTCTCAGCCATTTTTGTTAGCTCTACTTTAAAGTGGGATTTACAGTTAGAGTGGAAGAAATTCAAGTAAGGTTACAACTGATTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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