Basic Information
VIS ID
TVIS44008901
Fusion event
HTLV-1-LINC01500 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
59356320/58889602 (Hg38)
End
59356320/58889602 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA14B
Target gene
LINC01500
Nearest miRNA
hsa-mir-208a/Upstream/4011409; hsa-mir-1185-1/Downstream/757360;
Nearest TSS
ENST00000550708/Upstream/61314; ENST00000556026/Downstream/4564;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/242680, chr14-CpG: 130/Downstream/298310
Upstream sequence
cagggtctggggggtctgggggagggatagcattaggagatatacctaatgtaattgatgagttaatggatggagcaaaccaacatggcacatctatacc
Downstream sequence
tatgtaacaaacctgcacgttgggcacatgtaccctagaacttaaagtataataataaaaaaTAATAATTAAAAAAGTCCAGAGTCAAGTGTTGACACTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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