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TVIS44008917
Basic Information
VIS ID
TVIS44008917
Fusion event
HTLV-1-TNPO1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
72203394/72907567 (Hg38)
End
72203394/72907567 (Hg38)
Orient
-
Location type
Intronic
Target gene
TNPO1
miRNAs that regulate target gene
hsa-mir-210-3p
;
hsa-mir-155-5p
;
hsa-mir-124-3p
;
hsa-mir-34a-5p
;
hsa-mir-21-5p
;
hsa-mir-16-5p
;
hsa-mir-92a-3p
;
hsa-mir-18a-5p
;
hsa-let-7b-5p
;
hsa-mir-23a-3p
;
hsa-mir-27a-3p
;
hsa-mir-101-3p
;
hsa-mir-181a-5p
;
hsa-mir-181b-5p
;
hsa-mir-181c-5p
;
hsa-mir-23b-3p
;
hsa-mir-27b-3p
;
hsa-mir-130a-5p
;
hsa-mir-144-3p
;
hsa-mir-181d-5p
;
hsa-mir-513a-5p
;
hsa-mir-4262
;
hsa-mir-23c
;
hsa-mir-4310
;
hsa-mir-7157-5p
;
hsa-mir-648
;
hsa-mir-4468
;
hsa-mir-3591-5p
;
hsa-mir-1245b-3p
;
hsa-mir-548ao-5p
;
hsa-mir-548ax
;
hsa-mir-6081
;
hsa-mir-32-5p
;
hsa-mir-92b-3p
;
hsa-mir-139-5p
;
hsa-mir-190a-3p
;
hsa-mir-338-5p
;
hsa-mir-640
;
hsa-mir-1277-5p
;
hsa-mir-5011-5p
;
hsa-mir-6074
;
hsa-mir-6076
;
hsa-mir-6797-3p
;
hsa-mir-151a-3p
;
hsa-mir-4426
;
hsa-mir-4647
;
hsa-mir-4662b
;
hsa-mir-374a-5p
;
hsa-mir-4643
;
hsa-mir-4789-3p
;
hsa-mir-548d-3p
;
hsa-mir-548h-3p
;
hsa-mir-3613-3p
;
hsa-mir-548z
;
hsa-mir-548ac
;
hsa-mir-548bb-3p
;
hsa-mir-4742-3p
;
hsa-mir-20a-3p
;
hsa-mir-466
;
hsa-mir-513a-3p
;
hsa-mir-513c-3p
;
hsa-mir-3606-3p
;
hsa-mir-5585-5p
;
hsa-mir-5096
;
hsa-mir-410-3p
;
hsa-mir-3681-3p
;
hsa-mir-216a-3p
;
hsa-mir-128-3p
;
hsa-mir-7702
;
hsa-mir-4775
;
hsa-mir-5588-5p
;
hsa-mir-4799-3p
;
hsa-mir-4720-5p
;
hsa-mir-6868-5p
;
hsa-mir-8083
;
hsa-mir-3128
;
hsa-mir-3191-5p
;
hsa-mir-6728-3p
;
hsa-mir-142-3p
;
hsa-mir-6891-5p
;
hsa-mir-3173-3p
;
hsa-mir-4428
;
hsa-mir-802
;
hsa-mir-8485
;
hsa-mir-7-2-3p
;
hsa-mir-7-1-3p
;
hsa-mir-5688
;
hsa-mir-495-3p
;
hsa-mir-4668-5p
;
hsa-mir-103a-2-5p
;
hsa-mir-607
;
hsa-mir-3671
;
hsa-mir-505-3p
;
hsa-mir-140-3p
;
hsa-mir-195-3p
;
hsa-mir-16-2-3p
;
hsa-mir-6739-3p
;
hsa-mir-4677-5p
;
hsa-mir-7156-5p
;
hsa-mir-4273
;
hsa-mir-192-3p
;
hsa-mir-22-5p
;
hsa-mir-2116-5p
;
hsa-mir-942-5p
;
hsa-mir-1273g-3p
;
hsa-mir-1285-3p
;
hsa-mir-196a-3p
;
hsa-mir-3187-5p
;
hsa-mir-4252
;
hsa-mir-4793-3p
;
hsa-mir-508-5p
;
hsa-mir-5189-5p
;
hsa-mir-612
;
hsa-mir-6512-3p
;
hsa-mir-661
;
hsa-mir-6720-5p
;
hsa-mir-6849-3p
;
hsa-mir-6860
;
hsa-mir-766-3p
;
hsa-mir-7703
;
hsa-mir-939-3p
Nearest miRNA
hsa-mir-10397/Upstream/28904; hsa-mir-103a-1/Downstream/9932588;
Nearest TSS
ENST00000502646/Upstream/6693;
ENST00000507345/Downstream/46707;
Nearest CpG islands
None/Target,
chr5-CpG: 87/Upstream/58572
,
chr5-CpG: 128/Downstream/47788
Upstream sequence
TTCTACACAGATGGATTAACTGCCCTCTGTGAATTCACATGAACGTTCATAAATGGCCAAAACTTGGCATGATTGGGTAGTAGAGTTCTGTTTGTAAAAG
Downstream sequence
GACCACTATCAGGTAACAGTTTAAATCTCCCAGTAATCTTACCTTATTTCTTAATATCCTTTTTATCATTAAAACTGTTTAGCATAGAAAAAAGTTCCTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL73
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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