Basic Information
VIS ID
TVIS44008938
Fusion event
HTLV-1-PHACTR2-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
143885747/143564610 (Hg38)
End
143885747/143564610 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
PHACTR2-AS1
Nearest miRNA
hsa-mir-10398/Upstream/2880727; hsa-mir-1202/Downstream/7538065;
Nearest TSS
ENST00000381078/Upstream/2579; ENST00000545919/Downstream/43570;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/26996, chr6-CpG: 59/Downstream/113357
Upstream sequence
CCCATGCACATTTATGGGAATTCATTAGAGGGGGAAGCCTGGATTTAAAATTTCCCTCCATGAAACAGTTAAAGATCAAGAGGTGAATCGTGTGGGATAT
Downstream sequence
GAAGCATGTCATGGCTGAGCTGCTGACGAGGCCTCGGCTGTGCTTTGCATCATGTAAGGGCTCAGCACCCTGAGAAGGTGCCTGGTAAATGCCACTGGCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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