Basic Information
VIS ID
TVIS44008939
Fusion event
HTLV-1-GAS1RR integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
89565312/86950397 (Hg38)
End
89565312/86950397 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
GAS1RR
Nearest miRNA
hsa-mir-101-2/Upstream/2980540; hsa-let-7a-1/Downstream/1795439;
Nearest TSS
ENST00000422679/Upstream/1698; ENST00000623052/Downstream/91729;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1614, chr9-CpG: 18/Downstream/61197
Upstream sequence
tttctccctacctttacatccttactactcagatcaaaaggcagagtataatccccttccccttgagtcttgggtaggccttactgactttgaccaatag
Downstream sequence
gacatagtgaaagtgactgacattctggggcctccaaggctagatcacaagaagccttgcagcttctactcgggccttgtattagtccgttttcacactg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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