Basic Information
VIS ID
TVIS44008959
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
113317272/113981575 (Hg38)
End
113317272/113981575 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/3467660; hsa-mir-103a-1/Downstream/2274168;
Nearest TSS
ENST00000502646/Upstream/390417; ENST00000512927/Downstream/74431;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/467290, chr5-CpG: 76/Downstream/73799
Nearby gene
KCNN2(+380744) ;
Upstream sequence
attttgttacttacacagaatgtgtaatgtagtcaccaagtctgggtatttggggtgttcatcactttgggcatttgtcattttatgtattgggaaaaat
Downstream sequence
tcaagtcttctcttctagttacttgtgaatagtgttgcaataaatgcactagtgcagttatctcttggatatactcatttattttctttaggatagatac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate