Basic Information
VIS ID
TVIS44008974
Fusion event
HTLV-1-SNAI3-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
88738300/88671892 (Hg38)
End
88738300/88671892 (Hg38)
Orient
-
Location type
ncRNA_exonic
Target gene
SNAI3-AS1
Nearest miRNA
hsa-mir-11401/Upstream/202861; hsa-mir-4722/Downstream/44386;
Nearest TSS
ENST00000527434/Upstream/8512; ENST00000568633/Downstream/1504;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/7890, chr16-CpG: 21/Downstream/9447
Upstream sequence
gtctgttgttcctcttgaagtggccggctcacctcattcCTGCCAAGACCCAGGTCCGTGTTCTCACAGTGCTGCCATCTTTCCTCCGTGTGAGCGTGGG
Downstream sequence
CTGTGCGGAGAGTGGACCTCGGTGTGTGCGGGGCTGCGTGCACTGCCATCGCTCCCTCTACACGAGCCGGCGTGGACCCAGGGCTGAGCTGTGACCACGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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