Basic Information
VIS ID
TVIS44008994
Fusion event
HTLV-1-chr19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
47930179/47426922 (Hg38)
End
47930179/47426922 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/199901; hsa-let-7e/Downstream/1582984;
Nearest TSS
ENST00000633603/Upstream/7399; ENST00000593284/Downstream/5646;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/7402, chr19-CpG: 62/Downstream/3116
Nearby gene
SLC8A2(-1100) ;
Upstream sequence
CACTGCAGATCAGTGCACCGTCTGCCCCTACACCTTCCACAAACCTGTTCTCATCAAGGCCTAAAGCCAAAGGTCGAtttttttttttttttggtagtgg
Downstream sequence
ggagacagggtttttctctgtcactcaggctggagtgcagtggtgcagtcctagctcacggcagcctcgacctcctgggctcaagcaatcctcctgcttc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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