Basic Information
VIS ID
TVIS44009002
Fusion event
HTLV-1-LOC101929210 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
95107978/94186827 (Hg38)
End
95107978/94186827 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA4E
Target gene
LOC101929210
Nearest miRNA
hsa-mir-12113/Upstream/6886244; hsa-mir-1243/Downstream/4810560;
Nearest TSS
ENST00000502981/Upstream/358074; ENST00000506089/Downstream/20729;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/351668, chr4-CpG: 54/Downstream/20679
Upstream sequence
ctcccagttctctcacccatgtgtagttcctacccacactgcactaggagtagtctctgtgaccactggaatacagtagaagtgatggcatgtcagtagt
Downstream sequence
gacattcagttataaaagacactgcagcttttattaccctcttttcagatcccttgttctgggtgaagatgctagctacgataggcaggctcgctgctga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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