Basic Information
VIS ID
TVIS44009003
Fusion event
HTLV-1-LINC02267 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
97517441/96596290 (Hg38)
End
97517441/96596290 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4E
Target gene
LINC02267
Nearest miRNA
hsa-mir-12113/Upstream/9295707; hsa-mir-1243/Downstream/2401097;
Nearest TSS
ENST00000502981/Upstream/285558; ENST00000517407/Downstream/524411;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1046447, chr4-CpG: 19/Downstream/1547161
Nearby gene
PDHA2(+754816) ;
Upstream sequence
agggacccaaccttatttttttccaaatagaAAATGTTTCCTATATTATTTTCTAATTAACCACTGAAATCTCCAGTGATGTGACACATCTGCTGTATAA
Downstream sequence
TATTCTATATGTTTATATATAATCAGTTCTATTTATTAGTGCTGTGGACTTTCTACACTACTCCTTTTGTCTGTCCATTTATGAAGACAGCATACTCTTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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