Basic Information
VIS ID
TVIS44009013
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
87856973/87147255 (Hg38)
End
87856973/87147255 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/8607946; hsa-mir-1202/Downstream/3165487;
Nearest TSS
ENST00000381078/Upstream/51849; ENST00000392985/Downstream/5578;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/209266, chr6-CpG: 86/Downstream/4553
Nearby gene
ZNF292(+8296) ;
Nearest cancer related gene
ZNF292(TSG, +8296) ;
Upstream sequence
cctgggcaacagagggaaactatctttcaaaaaagaagaagaaggaggaggaggaggaggaggagaagTAGTTATGCTTTTAAAGATACATTTTAACATC
Downstream sequence
GAAGTTAATAAACAATTTCAAGCACAGTATATTTGTGTAATTTTATATTAATGTTAAGAGTTGCTTAAAATAGTATCTGATTTTAACTGTGTATACCTTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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