Basic Information
VIS ID
TVIS44009026
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
14342647/14189713 (Hg38)
End
14342647/14189713 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/1273795; hsa-let-7i/Downstream/3483586;
Nearest TSS
ENST00000382841/Upstream/207756; ENST00000538329/Downstream/26877;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/207710, chr12-CpG: 77/Downstream/377601
Nearby gene
ATF7IP(+175919) ;
Upstream sequence
GACTTGTAGACTAGATAATTACCAATCAAATAGGCCACTAAGAAGTCCAGAACTTAGTATCTCTGGCTTTATCATAATTGCCTGAACCTGCAGCTGTTTC
Downstream sequence
CTATGCATCCTAGGCAGGGATAACCTATAGTCTGAAGGAACTTGCCCTACTTTAAACTGCCCGCCAGTGCTCTTTGCAGaaaaaaaaaaaaaaaaaaaaT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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