Basic Information
VIS ID
TVIS44009033
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
161816264/160959753 (Hg38)
End
161816264/160959753 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-128-1/Upstream/551871; hsa-mir-10b/Downstream/7623190;
Nearest TSS
ENST00000437798/Upstream/465959; ENST00000477952/Downstream/177155;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/465893, chr2-CpG: 39/Downstream/200619
Nearby gene
TANK(+177202) ;
Nearest cancer related gene
TANK(TSG, +177202) ;
Upstream sequence
AGGGGGCATCACGAGTGGTCCCAGCAAGTATATGTACCCTGAGTCTTAGACCCTTATCATTAATTTCCATAACTCTAACTTCCAGGCATTAGATCAAAGC
Downstream sequence
CCATTGTGTCAGGTGGGCATAGTTGTTGGTGTTTACTCTCTGAAGTGCCTCGCCTCCAGAGGCTATGTATGGAATGTAGCAGTAATGAGATAACTAAGAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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