Basic Information
VIS ID
TVIS44009038
Fusion event
HTLV-1-LOC107986284 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
65648757/64783039 (Hg38)
End
65648757/64783039 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107986284
Nearest miRNA
hsa-mir-12113/Upstream/3860355; hsa-mir-1243/Downstream/1493785;
Nearest TSS
ENST00000502981/Upstream/373571; ENST00000509473/Downstream/241446;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1433173, chr4-CpG: 32/Downstream/886436
Nearby gene
LINC02232(-131242) ;
Upstream sequence
CCCGCCATTCTTTCCCCTAACATTGGTATATCCTCTTTATGAAGAAAACCGTAAAGAACAAGAGTTAATTCATGCTGCATCTGATTCATCTCTGAGCTAG
Downstream sequence
CATTGCTTTGATCAAGGTACTGTTTCTTTGCGGAGTAGATTTAAATGCCAACTGATTTCAAACCAGTAGTGCTTTAAAGCCCCTTTGCTTGTCTTATTTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate