Basic Information
VIS ID
TVIS44009057
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
15050803/15050804 (Hg38)
End
15050803/15050804 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3156-2/Upstream/220562; hsa-mir-1-2/Downstream/6632714;
Nearest TSS
ENST00000575820/Upstream/72065; ENST00000583946/Downstream/15794;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/50261, chr18-CpG: 29/Downstream/114306
Nearby gene
LINC01443(No orient, 77048)
Upstream sequence
AATTTCAAGAGCACTTATATAGACTGAATGTTGACACAAGAAGTAGTTTTTGCATGAACATTTTGAACATTATCTTGGAATTAGAAGTAGTTTTAAGTCA
Downstream sequence
TTTTCCCCTCtgtattggtttcctgctgcctctgtaacaaattactggaaacttggtggcttaaacaatagaaatttattcttttacagttctggatgtc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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