VISDB Viral Integration Site DataBase

VIS ID

TVIS44009068

Fusion event

HTLV-1-CLOCK integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

q12

Reference genome

Start

End

56405414/55539247 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-141-3p ; hsa-mir-182-5p ; hsa-mir-106b-5p ; hsa-mir-142-3p ; hsa-mir-26b-5p ; hsa-mir-21-5p ; hsa-mir-124-3p ; hsa-mir-152-3p ; hsa-mir-34a-5p ; hsa-mir-20a-5p ; hsa-mir-203a-3p ; hsa-mir-526b-5p ; hsa-mir-4635 ; hsa-mir-5571-5p ; hsa-mir-4423-3p ; hsa-mir-6826-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-3622a-5p ; hsa-mir-5582-5p ; hsa-mir-552-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-5089-5p ; hsa-mir-6728-5p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-1290 ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-5583-5p ; hsa-mir-3129-3p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-580-3p ; hsa-mir-4461 ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-129-5p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-93-5p ; hsa-mir-17-5p ; hsa-mir-107

Nearest miRNA

hsa-mir-12113/Upstream/2826500; hsa-mir-1243/Downstream/5383372;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/142911, chr4-CpG: 144/Downstream/6579

Upstream sequence

tcatttgaacccaggaggcagaagctgcagtgagctcagatcacgccactgcactccagcctaagcaacagaacgagactgtctcaaaaaaacaacaaca

Downstream sequence

acaacaacaaaaaaaacaccaaaaaccacttcaaaaaaggtgaaactgccgtgcatggtggctcacacctatacccagcactttgggaggccaaggtggg