Basic Information
VIS ID
TVIS44009081
Fusion event
HTLV-1-LOC101929174 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
88144397/88411229 (Hg38)
End
88144397/88411229 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC101929174
Nearest miRNA
hsa-mir-10392/Upstream/234636; hsa-let-7a-2/Downstream/2144545;
Nearest TSS
ENST00000527297/Upstream/73442; ENST00000531994/Downstream/93347;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/73355, chr11-CpG: 96/Downstream/97313
Nearby gene
CTSC(-73442) ;
Upstream sequence
GATGCTCCTAAATTACAGCCATTATATCGCAGGAGATAGAACATATACGAGGCACAATGGCAAAGCATAGGATCTATGTTTTAACTAATGAATGGGAAAT
Downstream sequence
AGGCtccaaaagaagattgcccattaaagccatccccttgagaggctattaatgaattccaaagatgttgcctttccttaaagcttttttggaacttgta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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