Basic Information
VIS ID
TVIS44009090
Fusion event
HTLV-1-chr22 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
47822397/47426647 (Hg38)
End
47822397/47426647 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA22A
Nearest miRNA
hsa-let-7a-3/Upstream/1312879; hsa-mir-12114/Downstream/847717;
Nearest TSS
ENST00000624155/Upstream/81078; ENST00000426452/Downstream/60441;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/213075, chr22-CpG: 25/Downstream/782698
Upstream sequence
aaacttattgctgagtagatagaaaataaaaaaaaattatcctgataatgtgaaaccctaaaccaatgctcatgtggttttgcattctgaactcatatcc
Downstream sequence
actgtgataaaaaggagaaaaaaaacaaaacctcaagggagaaattattttaaagttgtctatcctgagctggtagcaacccaagagaatacagattccc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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