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TVIS44009096
Basic Information
VIS ID
TVIS44009096
Fusion event
HTLV-1-EIF4H integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
73606405/74192075 (Hg38)
End
73606405/74192075 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
EIF4H
miRNAs that regulate target gene
hsa-mir-24-3p
;
hsa-mir-941
;
hsa-mir-93-3p
;
hsa-mir-378a-3p
;
hsa-mir-185-5p
;
hsa-mir-149-5p
;
hsa-mir-10a-5p
;
hsa-mir-197-3p
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106a-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-651-3p
;
hsa-mir-1252-3p
;
hsa-mir-5093
;
hsa-mir-503-5p
;
hsa-mir-1252-5p
;
hsa-mir-2110
;
hsa-mir-4271
;
hsa-mir-4725-3p
;
hsa-mir-6828-5p
;
hsa-mir-6780b-5p
;
hsa-mir-370-5p
;
hsa-mir-452-3p
;
hsa-mir-4709-3p
;
hsa-mir-3611
;
hsa-mir-8080
;
hsa-mir-4699-5p
;
hsa-mir-4766-5p
;
hsa-mir-5092
;
hsa-mir-562
;
hsa-mir-4422
;
hsa-mir-374a-3p
;
hsa-mir-4777-5p
;
hsa-mir-526a
;
hsa-mir-523-5p
;
hsa-mir-522-5p
;
hsa-mir-520c-5p
;
hsa-mir-519c-5p
;
hsa-mir-519b-5p
;
hsa-mir-519a-5p
;
hsa-mir-518f-5p
;
hsa-mir-518e-5p
;
hsa-mir-518d-5p
;
hsa-mir-4305
;
hsa-mir-10b-3p
;
hsa-mir-4796-3p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-1245b-5p
;
hsa-mir-134-3p
;
hsa-mir-148b-5p
;
hsa-mir-194-5p
;
hsa-mir-3142
;
hsa-mir-3190-3p
;
hsa-mir-3202
;
hsa-mir-3660
;
hsa-mir-3691-5p
;
hsa-mir-376b-5p
;
hsa-mir-376c-5p
;
hsa-mir-3919
;
hsa-mir-4306
;
hsa-mir-4312
;
hsa-mir-4330
;
hsa-mir-4428
;
hsa-mir-4476
;
hsa-mir-4526
;
hsa-mir-4533
;
hsa-mir-4644
;
hsa-mir-4649-3p
;
hsa-mir-4663
;
hsa-mir-4752
;
hsa-mir-5008-5p
;
hsa-mir-552-3p
;
hsa-mir-6089
;
hsa-mir-628-5p
;
hsa-mir-6874-3p
;
hsa-mir-6876-5p
;
hsa-mir-7114-5p
;
hsa-mir-7160-5p
;
hsa-mir-8056
;
hsa-mir-8077
;
hsa-mir-196a-3p
;
hsa-mir-328-5p
;
hsa-mir-4742-5p
;
hsa-mir-625-5p
;
hsa-mir-6757-5p
;
hsa-mir-6768-5p
;
hsa-mir-6795-5p
;
hsa-mir-6885-5p
;
hsa-mir-6887-5p
;
hsa-mir-7109-5p
;
hsa-mir-8485
Nearest miRNA
hsa-mir-1183/Upstream/781; hsa-mir-10399/Downstream/403893;
Nearest TSS
ENST00000635602/Upstream/8253;
ENST00000491595/Downstream/7577;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/17064
,
chr7-CpG: 82/Downstream/61988
Upstream sequence
tcatcatgttagccaggatggtctcgatctcctgacctcgtgatccacctgcctcggcctcccaaagtgctgggattacaggcatgagccaccgcgcccg
Downstream sequence
gccCCCACCAACAGATTTGATGAGAGATCCTTGTTCATCTGCTTCACCAGCGTGGTGTGAGCTATTTGTTTCACGCTAGACATTGGTGGTCGAAATCATT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL20
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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