Basic Information
VIS ID
TVIS44009096
Fusion event
HTLV-1-EIF4H integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
End
73606405/74192075 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-24-3p ; hsa-mir-941 ; hsa-mir-93-3p ; hsa-mir-378a-3p ; hsa-mir-185-5p ; hsa-mir-149-5p ; hsa-mir-10a-5p ; hsa-mir-197-3p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-651-3p ; hsa-mir-1252-3p ; hsa-mir-5093 ; hsa-mir-503-5p ; hsa-mir-1252-5p ; hsa-mir-2110 ; hsa-mir-4271 ; hsa-mir-4725-3p ; hsa-mir-6828-5p ; hsa-mir-6780b-5p ; hsa-mir-370-5p ; hsa-mir-452-3p ; hsa-mir-4709-3p ; hsa-mir-3611 ; hsa-mir-8080 ; hsa-mir-4699-5p ; hsa-mir-4766-5p ; hsa-mir-5092 ; hsa-mir-562 ; hsa-mir-4422 ; hsa-mir-374a-3p ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-4305 ; hsa-mir-10b-3p ; hsa-mir-4796-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-1245b-5p ; hsa-mir-134-3p ; hsa-mir-148b-5p ; hsa-mir-194-5p ; hsa-mir-3142 ; hsa-mir-3190-3p ; hsa-mir-3202 ; hsa-mir-3660 ; hsa-mir-3691-5p ; hsa-mir-376b-5p ; hsa-mir-376c-5p ; hsa-mir-3919 ; hsa-mir-4306 ; hsa-mir-4312 ; hsa-mir-4330 ; hsa-mir-4428 ; hsa-mir-4476 ; hsa-mir-4526 ; hsa-mir-4533 ; hsa-mir-4644 ; hsa-mir-4649-3p ; hsa-mir-4663 ; hsa-mir-4752 ; hsa-mir-5008-5p ; hsa-mir-552-3p ; hsa-mir-6089 ; hsa-mir-628-5p ; hsa-mir-6874-3p ; hsa-mir-6876-5p ; hsa-mir-7114-5p ; hsa-mir-7160-5p ; hsa-mir-8056 ; hsa-mir-8077 ; hsa-mir-196a-3p ; hsa-mir-328-5p ; hsa-mir-4742-5p ; hsa-mir-625-5p ; hsa-mir-6757-5p ; hsa-mir-6768-5p ; hsa-mir-6795-5p ; hsa-mir-6885-5p ; hsa-mir-6887-5p ; hsa-mir-7109-5p ; hsa-mir-8485
Nearest miRNA
hsa-mir-1183/Upstream/781; hsa-mir-10399/Downstream/403893;
Upstream sequence
tcatcatgttagccaggatggtctcgatctcctgacctcgtgatccacctgcctcggcctcccaaagtgctgggattacaggcatgagccaccgcgcccg
Downstream sequence
gccCCCACCAACAGATTTGATGAGAGATCCTTGTTCATCTGCTTCACCAGCGTGGTGTGAGCTATTTGTTTCACGCTAGACATTGGTGGTCGAAATCATT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate