Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene449027324521299545683686452473344525017945253923452565554529119345292935452428074524414545244696452458504527798745278281452849524528516745293209
Basic Information
VIS ID
TVIS44009106
Fusion event
HTLV-1-SLC14A2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
42873174/45293209 (Hg38)
End
42873174/45293209 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC14A2
Nearest miRNA
hsa-mir-1-2/Upstream/323043; hsa-mir-122/Downstream/2087287;
Nearest TSS
ENST00000575820/Upstream/80214; ENST00000323329/Downstream/142088;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/229237, chr18-CpG: 37/Downstream/482144
Upstream sequence
AGGAGAACTCTAAACATATTTAAGGCAGTAATTACATTATTAGAGTAAGCAGAAAATGTCCCATGGAGAACCTTTTTTGACGTGCAAAACACTCCAGTGT
Downstream sequence
GTGTGCTTAGGTGTATGAGTTTATAGCCACATTTCAGTTTTAAGTCTGGTGTTATttcattcattcattcattcatgtattcattcataaacacttattg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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