Basic Information
VIS ID
TVIS44009125
Fusion event
HTLV-1-LOC107985447 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p12
Reference genome
GRCh37/hg19
Start
119391129/118848506 (Hg38)
End
119391129/118848506 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107985447
Nearest miRNA
hsa-mir-101-1/Upstream/1753778; hsa-mir-1182/Downstream/27002081;
Nearest TSS
ENST00000473358/Upstream/663283; ENST00000423984/Downstream/65619;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/663032, chr1-CpG: 27/Downstream/131256
Nearby gene
TBX15(-34537) ;
Upstream sequence
AGTTTTTCACTTTCCATATGAAAAACAGTTATATTTTCCAAGTCAAGCCAGTCTCCCTCATGGAAATTAAACCACCTTGGATTCTGGTAAGCTTGATATT
Downstream sequence
CTTTTTATTAAAGCACTAAATTTGTCTTTATATAACAGAGGGAAAACTTGCCTCCCAGAACTAATACATGTTTTAATATCCATACCGATAATAATTCCTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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