Basic Information
VIS ID
TVIS44009140
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
GRCh37/hg19
Start
242866563/242703261 (Hg38)
End
242866563/242703261 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/1570915; hsa-mir-3124/Downstream/642915;
Nearest TSS
ENST00000473358/Upstream/178565; ENST00000439562/Downstream/304207;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/177881, chr1-CpG: 43/Downstream/187034
Nearby gene
PLD5(-178565) ;
Upstream sequence
AAAGTCAGCAGTGGAGAAGCTATGGAGTAATTCCATAATACTAGCACCAATTTAATTTAGAATAATGGGAGCAGAGAGCACCAGAATACATAAGCCACGA
Downstream sequence
GGCACTATTCTACTAGGGGAATACTTCAGAATGAGAATAATTTTTGTGAATTGAATACTTTTGAGATGTTGGACAATTCCAAAAAGTTCTCATCCTTCAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate